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مقاله Abstract


Title: Optical Coherence Tomography Angiography Analysis of Foveal Microvasculature
Author(s): Khalil Ghasemi Falavarjani, Hamideh Shenazandi, Dariush Naseri, Pasha Anvari, Pegah Kazemi, Sayyed Amirpooya Alemzadeh
Presentation Type: Poster
Subject: Retina and Retinal Cell Biology
Others:
Presenting Author:
Name: Pasha Anvari
Affiliation :(optional) Eye Research Center and Department of Ophthalmology, Rassoul Akram Hospital, Iran University of Medical Sciences
E mail: anvari.p@iums.ac.ir
Phone: 88010558
Mobile: 09122490767
Purpose:

: To report the normal characteristics and correlations of the foveal microvascular networks using optical coherence tomography angiography (OCTA) in a healthy Iranian population.

Methods:

In this prospective observational case-series, enface 3x3 OCTA images were obtained using AngioVue software. Foveal avascular zone (FAZ) area, central foveal point thickness and inner retinal thickness at the foveal center and the vascular density of the superficial retinal capillary plexus (SCP) and deep retinal capillary plexus (DCP) in the fovea were recorded.

Results:

Seventy-five normal eyes of 75 subjects were studied. Mean FAZ area was 0.33±0.10 (range 0.13 - 0.67) mm2 in SCP and 0.50 ± 0.13 (range 0.19-0.94) mm2 in DCP. Mean SCP vessel density was 29.1±5.4 % (range 4.7-40.2) in the fovea. Mean DCP vessel density was 27.1±5.7% (range 15.0-45.2) in the fovea. Mean central subfield and parafoveal retinal thickness was 247.1±20.8 (range 192-300) µm and 317.9±15.0 (range 279-357) µm, respectively. Mean CFPT was 204.8±13.8 (range 185.5-245.5) µm. The FAZ area at SCP level was associated with central subfield thickness (beta= -.67, P<0.001, R2=0.51). The FAZ area at DCP level was associated with age and central subfield thickness (beta=0.63, P<0.001 and beta=-0.50, P<0.001, respectively, R2=0.53).

Conclusion:

OCTA is a reliable, non-invasive tool for analyzing foveal microvasculature at superficial and deep plexuses. FAZ size is inversely associated with foveal thickness.

Attachment: 48octa.pptx





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